Dr. Lena Arévalo, M.A.

Postdoctoral Researcher (Habilitant)
Expert at EDU since April 2020
Dr. Lena Arévalo, M.A.


Aug 2018 – present: Postdoctoral researcher (Habilitant), University of Bonn, Medical school, Department of developmental pathology, Bonn, Germany

The role of cleaved-Protamine 2 in sperm chromatin dynamics.

Aug 2016 – July 2018: Postdoctoral researcher, Oklahoma State University, Campbell lab, Department of Integrative Biology, Stillwater, OK, USA

Effects of hybrid loss of imprinting on brain and behavior, Supervision: Polly Campbell

university education

2009 – 2015: PhD Molecular evolutionary biology (Molecular Biology Faculty), Universidad Autónoma de Madrid, Spain

2003 – 2009: Master (Magister, M.A., one-tier program) Biological Anthropology (Evolutionary Genetics), Johannes Gutenberg-Universität Mainz, Mainz, Germany


2020: FEMHABIL supplementary research grant, University of Bonn, Medical School

2018 – 2021: Deutsche Forschungsgemeinschaft Research Grant. The role of cleaved-protamine 2 in sperm chromatin dynamics.

2010 – 2015: Fellowship: JAE predoctoral (CSIC) co-funded by the European Social Fund

Selection of publications

(Married name: Arévalo, Birth name: Lüke)

Lena Arévalo, Polly Campbell (2020) Placental effects on maternal brain revealed by disrupted placental gene expression in mouse hybrids. Proceedings of the Royal Society B: Biological Sciences 287:20192563. DOI: https://doi.org/10.1098/rspb.2019.2615

Arévalo L, Brukman NG, Cuasnicú PS, Roldan ER (2020) Evolutionary analysis of genes coding for Cysteine-RIch Secretory Proteins (CRISPs) in mammals. BMC Evolutionary Biology. 20:1-3.

Schneider S, Shakeri F, Trötschel C, Arévalo L, Kruse A, Buness A, Poetsch A, Steger K, Schorle H (2020) Protamine-2 Deficiency Initiates a Reactive Oxygen Species (ROS)-Mediated Destruction Cascade during Epididymal Sperm Maturation in Mice. Cells. 9:1789.

Sina Jostes, Martin Fellermeyer, Gina Merges, Lena Arévalo, Glen Kristiansen, Daniel Nettersheim, Hubert Schorle (2020) Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumour fate. International Journal of Cancer 146:1592-605.

Kaiser F, Kubaczka C, Graf M, Langer N, Langkabel J, Arévalo L, Schorle H (2020) Choice of factors and medium impinge on success of ESC to TSC conversion. Placenta 90:128-37

Polly Campbell, Lena Arévalo, Heather Martin, Charles Chen, Shuzhen Sun, Ashlee Rowe, Michael Webster, Jeremy Searle, Bret Pasch (2019) Vocal divergence is concordant with genomic evidence for strong reproductive isolation in grasshopper mice (Onychomys). Ecology and Evolution 9:12886-96

Brian Couger, Lena Arévalo, Polly Campbell (2018) A high quality genome for Mus spicilegus, a closerelative of house mice with unique social and ecological adaptations. G3: Genes, Genomes, Genetics. DOI: 10.1534/g3.118200318

Lena Lüke, Maximiliano Tourmente, Hernan Dopazo, Francois Serra, Eduardo R S Roldan (2016) Selective Constraints on Protamine 2 in Primates and Rodents. BMC Evolutionary Biology 16:21. DOI:10.1186/s12862-016-0588-1.

Lena Lüke, Maximiliano Tourmente, Eduardo R S Roldan (2015) Sexual selection on protamine 1 in mammals. Molecular Biology and Evolution 3:174-184. DOI: 10.1093/molbev/msv209.

Lena Lüke, Alberto Vicens, Maximiliano Tourmente, Eduardo R S Roldan (2014) Evolution of Protamine Genes and Changes in Sperm Head Phenotype in Rodents. Biology of Reproduction 2:115956. DOI:10.1095/biolreprod.113.115956.

Lena Lüke, Polly Campbell, María Varea Sánchez, Michael W Nachman, Eduardo R S Roldan (2014) Sexual selection on protamine and transition nuclear protein expression in mouse species. Proceedings of the Royal Society B: Biological Sciences 281:20133359.DOI:10.1098/rspb.2013.3359.

Highlighted in: http://news.sciencemag.org/biology/2014/04/scienceshot-how-make-speedy-sperm

Highlighted in: https://www.sciencenews.org/blog/scicurious/males-compete-all-way-sperm-shape


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